One of the reasons why we often say that drug testing is not credible is that all drugs do not stay in the human body for the same amount of time. In fact, some drugs remain in urine, blood, and hair longer than cocaine, ice and other potent drugs, such as marijuana.
Cocaine and its byproducts generally stay in the human system for one to four days after last use, but the substances can linger in the system even longer with chronic or heavy use of the drug.
Up to 90 days
Cocaine is detectable in a urine test for 3-4 days.
A blood test will detect cocaine for 1-2 days.
A saliva test will detect cocaine from 1-10 days.
If it is necessary to detect the history of drug abuse, hair is an ideal biological test material. A hair test will detect cocaine for up to 90 days.
Cocaine is a local anesthetic (painkiller) and a powerful stimulant of the central nervous system (nerves that control activities in our body). Cocaine can be inhaled, injected or smoked (crack).
The chemical name for the pure cocaine is 8-methyl-3-(benzyloxy) 8-azabicyclo[3,2,1]octane-2-carboxylic acid methyl ester. Molecular formula C17H21NO4, molecule.
Cocaine abuse methods include nasal aspiration/spraying, smoking, and injection. Generally, the dose is used, and the nasal inhalation is 10-30 mg/time (individually reported to reach 50-200 mg, the typical user will inhale the dose separately with two nostrils); if using the injection method 10-20 mg/time.
The extent of the action of these toxins into the human body is closely related to the way they enter.
The bioavailability of cocaine by intravenous injection (the amount of drug absorbed by the body) is 100%, oral administration is 20%-30%, and nasal suction is 20%. %-30%, fuel absorption is 6%-32%.
Among them, the most common route is nasal inhalation, one nostril is blocked, and the other nostril is used to inhale cocaine crystal powder.
The cocaine powder is divided into a plurality of rows or columns by sharps such as a razor, and one gram of cocaine can be divided into about 25-50 rows, each of which acts 3-5 cm, and contains about 25-30 mg of commercially available cocaine.
This medicine is then inhaled through a straw made from US dollar bills or by means of a cocaine “spoon”. In this way, the drug is actually absorbed through the mucosa, and the peak plasma concentration can be reached in about 15 minutes, but the clinical onset time is very fast.
Intravenous use of cocaine hydrochloride for approximately 3-5 minutes. If you use the most popular free cocaine in the black market, you can have a strong euphoria in 1min when inhaled for 5-10min. Its half-life is also different.
The average half-life of intravenous injection was 45 min, the oral half-life was 48 min, and the half-life from nasal inhalation was 75 min.
The lethal dose is 0.5~1g orally, 30mg orally for allergy, 30mg for intramuscular or mucosal administration, and lethal blood concentration iare0.9-21mg/L.
Cocaine can be absorbed quickly no matter how it enters the body. The difference is only the length of time and the strength of utility. Its metabolism is mainly achieved through liver tissue and plasma.
After taking cocaine drugs, although the suckers feel very happy and are filled with these pleasures, they seem to have been abnormal and appear to be mentally problematic to outsiders.
However, the smokers cannot feel it. As they were controlled by the illusion created by cocaine drugs, they had lost themselves.
People who use cocaine drugs have a slightly longer period of cocaine use. People with deeper levels of cocaine drugs do have some common physical characteristics.
Due to the long-term malnutrition and the direct effect of cocaine drugs on endocrine, the levels of sex hormones in people who take cocaine drugs are disordered and declining.
As a result, the performance of various premature agings, such as
When using cocaine manifests its psychostimulatory effect. A person experiences euphoria, a powerful burst of energy. There are self-confidence and a sense of comfort.
In order to re-experience this range of pleasant sensations, the drug begins to be used again and again. Someone manages to stay at the stage of episodic use for several years, someone becomes a drug addict in a few months.
If they have formed a psychological dependence in the absence of the drug in the blood of a person’s thoughts keep coming back to pleasant memories of narcotic intoxication. There is an obsessive desire to take a dose again to experience euphoria.
The use of powder occurs more and more often. At some point, dependence on psychostimulant becomes so pronounced that develop real “cocaine binges” when dependent drug use non-stop for several days. All this time he can not eat and not sleep. After the exhaustion of the body comes restless sleep, after which the depressed mood and an insatiable desire to take the drug.
Physical dependence on cocaine is slow and mild. Its formation is indicated by the following symptoms that occur after drug withdrawal: depression, a delirium of persecution, sleep disorders.
The first drug addicts chewed the leaves of the Coca plant.
The modern drug is used by addicts in the form of a white powder containing 80-95% of the active substance. This powder-cocaine hydrochloride, scattered on a horizontal surface in the form of tracks and retracted nose. Through the capillaries, the drug enters the bloodstream, and then with its current to the brain, where it has a psychostimulatory effect.
An alternative to the salt of cocaine is Coca paste, which is extracted at the first stage of the step process of producing a pure drug. It contains 40-80% of the active substance and is used for Smoking (usually mixed with tobacco or marijuana).
Another common way to use cocaine is to smoke crack. This kind of drug has the appearance of dense pinkish pieces. The name of crack was due to the characteristic sound that occurs when Smoking a cigarette.
Speedball is a mixture of cocaine and heroin used for intravenous administration. It has a rapid destructive effect on the psyche and body.
Cocaine interferes once in three neurotransmitter systems of the body: serotonin, dopamine, and noradrenaline responsible for many effects including the feeling of pleasure, psychological comfort, contentment themselves. Achieving peak sensations after taking a dose very quickly deprives a person of motivation to achieve goals, develop, build relationships with others. There is a rapid social exclusion, a rapidly developing mental changes, because of which the snowbirds are degraded and isolated from society.
Since cocaine increases the release of stress hormones, the risk of cardiovascular catastrophes-heart attacks and strokes – increases by 20 times, heart rhythm disturbances, hypertensive crises, aortic wall stratification occur. All of these can lead to sudden death. Long-term use of psychostimulant causes severe heart disease (hypertrophic cardiomyopathy) and early atherosclerosis – the underlying cause of coronary heart disease and strokes.
Cocaine causes complete destruction of the nasal septum (inhalation through the nose). Its effect on the lungs leads to pulmonary bleeding, pneumothorax, non-infectious pneumonia (pneumonitis).
Similarly, the drug acts on the gastrointestinal tract, provoking the development of gastrointestinal bleeding and vascular thrombosis of the mesentery of the intestine with the development of necrosis (death) from emergency conditions.
In the case of the use of surfactants by expectant mothers, the risk of termination of pregnancy, intrauterine fetal death, birth of children with developmental defects increased dramatically, newborns are at high risk of stroke.
The formed psychological dependence says that the person is sick with drug addiction and needs treatment.
Many novice consumers, struggling with addiction, are trying to create a system of “restraints”, for example, spend a strictly certain amount of drug per month or make a promise to use it no more often than once every few weeks. Very quickly, mental dependence on the drug pushes them to deal with themselves, and the drug is used more and more often. In the end, there are repeated “cocaine binges”.
One dose of the drug does not last long – from 20 minutes to an hour, a maximum of two. Withdrawal usually develops after a “cocaine binge” and is characterized by a depressed and extremely anxious state up to deep depression and thoughts of suicide.
If you cancel the drug develops delusions of persecution. Man is looking for solitude, experiencing wolf hunger and a strong desire to sleep.
Overdose powder can lead to the death of patients. When it can occur:
If you suspect an overdose of the drug, you need to call an ambulance as soon as possible.
Cocaine is extracted: Researchers point out that drug dealers make cocaine, first by soaking coca leaves in petroleum derivatives such as kerosene, and then adding sodium carbonate, lime milk, or potassium permanganate, and filtering them to produce crude cocaine.
Cocaine, also known as coca cream. The coca paste is then combined with chloral hydrate, filtered and dried.
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How Long Does Cocaine Stay in Your System?
Long-term use of cocaine can cause lung diseases such as pneumonia and pulmonary haemorrhage.
The sucker’s lungs can be scarred. Repeated smoking of cocaine can also cause chronic pharyngitis, severe rhinitis, chest pain, difficulty breathing, high fever, and lack of oxygen.
The most prominent mental disorders caused by cocaine drugs are hallucinations and thinking disorders.
The bbehavioralcharacteristics of cocaine drug abusers revolve around the diversion of cocaine and even the loss of humanity for the consumption of cocaine drugs.
Intravenous cocaine drugs to abusers, bringing infectious complications, the most common pyogenic infections and hepatitis B, and worrying AIDS. In addition, it also damages the nervous system, the immune system, and is susceptible to various diseases.
Cocaine enters the central nervous system, which can quickly generate euphoria. The euphoria and mood-raising that can be trapped mainly depend on whether the plasma concentration is rising or falling because it is euphoric.
The decay rate is faster than the decrease in blood concentration. Cocaine is a convulsive agent. A single dose of cocaine can induce seizures, and repeated use can cause chronic epilepsy.
In addition, cocaine abuse can also cause intracranial haemorrhage, seizures, persistent or mechanical repetitive movements, ataxia and abnormal gait. The above abnormalities will gradually disappear after drug withdrawal.
Cocaine easily causes coronary artery stenosis and increases platelet agglutination. Theatrical catecholamine acts on a and receptors of the peripheral and coronary vessels simultaneously, increasing peripheral blood pressure and increasing coronary vascular resistance.
These changes can increase the risk of Heart disease risk. Studies have shown that the amount of cocaine entering the heart has a direct relationship with the death of experimental animals. In addition, cocaine causes
The nasal mucosa is absorbed quickly after snorting cocaine. Because of its irritation and contraction of blood vessels, it is easy to form nasal cavity ulcers, loss of sense of smell, nasal valve atrophy, nasal septum perforation.
Cocaine acts on the medullary respiratory center, bronchial smooth muscle, and pulmonary vessels, leading to respiratory complications such as dyspnea, alveolar hemorrhage, cough, fever, pulmonary edema, pulmonary asthma and interstitial.
Many cocaine abusers think that cocaine can increase sexual desire, but after serious addiction, they no longer pay attention to the pleasure of sexual intercourse and instead focus on how to satisfy their desire for cocaine.
After cocaine is injected intravenously or after inhalation, even if there is no stimulation of the sex organs, excitement can be induced or even spontaneous ejaculation. Sometimes it can even replace sexual partners.
Cocaine’s sexual excitement soon produces tolerance, and long-term abuse can lead to various sexual dysfunctions, including menstrual disorders, lactation, menopause, sexual excitement, and infertility.
How Long Does Cocaine Stay in Your System?
Intravenous injections of drugs can easily infect the immune system through the use of syringes infected with HIV, impairing the ability of the machine to withstand common opportunistic infections caused by AIDS.
Intravenous cocaine and sexually promiscuous patients may also transmit and contract hepatitis B virus, hepatitis, and sexually transmitted diseases (especially syphilis).
Effects on Pregnancy and Fetus Cocaine reduces sperm count and motility while increasing the number of abnormal spermatozoa.
Cocaine appears in the semen and may reduce the number of sperm, and increase the number of abnormal sperm. This can make it harder for you to get pregnant.
Treatment during the detoxification period. In general, no alternative or declining treatment is required during cocaine detoxification.
Therefore, antidepressants and dopamine receptor agonists should be used mainly during this period to treat mental and physical disorders and withdrawal reactions due to overdose.
Non-pharmacological treatment is a comprehensive treatment, including behavioural therapy, psychotherapy, rehabilitation, family therapy, group therapy and various preventive relapse treatments.
Non-pharmacological treatment is an indispensable and important process in the treatment of cocaine withdrawal. At the same time, it can effectively prevent relapse.
The study found that the main cause of relapse is that patients are psychologically eager to regain the euphoria when taking cocaine, so prevention of relapse should start with eliminating the patient’s “heart addiction.”
At the time of treatment, the therapist should analyze the various environmental, event, and human factors that induce relapse, and discuss and formulate corresponding solutions with them.
At the same time, patients should be encouraged to participate in regular self-help group activities. It enables it to gradually learn to deal with negative emotions and situations independently and to restore its social function.
In addition, family support and help are also essential to prevent relapse. Family members and drug addicts have the closest relationship.
As relatives, they open their hearts to drug addicts, embrace them with love and warmth, actively urge and help them to detoxify, patiently guide them out of the dark abyss of drug abuse, and rebuild confidence in life and Enthusiasm helps prevent relapsers from drug abusers.
Therefore, to stop cocaine addiction, it is best to go to the formal drug rehabilitation agencies for detoxification, especially for adolescents, their bodies are in the developmental stage, cannot withstand the pain caused by the dry ring; for long drug use, poison Those who are deeply addicted and whose individual willpower is not determined should also choose to go to a regular hospital for treatment.
About the method of detoxification after withdrawal of cocaine addiction, that is, the method of preventing relapse, patients should stay away from the places and friends who use drugs to avoid temptation, the room is comfortable and light, and the diet and living should be slow.
Return to normal, drink plenty of water, eat more beef, vegetables, fruits, eat more high vitamins to increase protein intake, do not eat spicy and irritating food, and insist on exercise, slowly return to normal life.